The GLP-1 landscape in six lines
- Two molecules dominate: semaglutide (Wegovy, Ozempic, the Wegovy tablet) and tirzepatide (Zepbound, Mounjaro). The brand names differ by approved indication, not by ingredient.
- Weight management vs type 2 diabetes is the split that decides coverage: Wegovy and Zepbound are approved for weight, Ozempic and Mounjaro for diabetes, and insurers police the difference.
- Three GLP-1 brands left the US market in 2024 — Victoza in April, Byetta and Bydureon BCise in October — for commercial rather than safety reasons.
- Oral options now exist and are FDA-approved: the Wegovy tablet and Foundayo (orforglipron), both from $149/month direct from the manufacturer.
- Compounded semaglutide and tirzepatide are NOT FDA-approved. The agency does not review them for safety, effectiveness, potency or purity, whichever pharmacy prepares them.
- The FDA declared both shortages resolved, which removed the legal basis most mass compounding rested on.
GLP-1 Medications
Compare FDA-approved and compounded GLP-1 medications. Pricing, side effects, savings cards, and provider availability.
All medications at a glance
Scan and compare — uniform cards, status badges, and lowest known partner price for each.
- FDA approved
Trulicity
dulaglutide
Type 2 diabetes glycemic control
Pricing varies by provider
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- FDA approved
Byetta
exenatide
Type 2 diabetes glycemic control
Pricing varies by provider
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- FDA approved
Bydureon BCise
exenatide ER
Type 2 diabetes glycemic control
Pricing varies by provider
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- FDA approvedIn shortage
Saxenda
liraglutide
Chronic weight management
Pricing varies by provider
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- DiscontinuedIn shortage
Victoza
liraglutide
Type 2 diabetes glycemic control
Pricing varies by provider
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- FDA approved
Rybelsus
semaglutide
Type 2 diabetes glycemic control
Pricing varies by provider
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- FDA approved
Ozempic
semaglutide
Type 2 diabetes glycemic control
Pricing varies by provider
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- FDA approved
Wegovy
semaglutide
Chronic weight management
Pricing varies by provider
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- CompoundedCash-pay only
Compounded Semaglutide
semaglutide (compounded)
Pricing varies by provider
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- FDA approved
Mounjaro
tirzepatide
Type 2 diabetes glycemic control
Pricing varies by provider
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- FDA approved
Zepbound
tirzepatide
Chronic weight management
Pricing varies by provider
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- CompoundedCash-pay only
Compounded Tirzepatide
tirzepatide (compounded)
Pricing varies by provider
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Browse by drug class
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GLP-1 oral (non-injectable)
Compounded GLP-1 medications
Compare GLP-1 telehealth providers
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- Sesame Care· from $208/moTop ratedTelehealth · online visit
- SkinnyRx· from $199/moCompounded not offered in AL, LA, MS — check before startingTelehealth · online visitCompounded · not FDA-approved
- Enhance MD· price shown after their intakeNo lab work to startRestricted in AL, AR, GA, HI, LA, MS, MO, ND, SC, TN, WV — check before startingTelehealth · online visitCompounded · not FDA-approved
- HealthRX· from $165/moLowest starting priceon the 12-month plan, $1,188 billed upfrontTelehealth · online visitCompounded · not FDA-approved